We are supporting several living evidence partnerships as we develop and test our model. Here we illustrate our approach through a focus on the Type 2 Diabetes Medicines Partnership.

For further details about Alive, please contact hello@aliveevidence.org

‍In partnership with Australian Living Evidence Collaboration (Monash University), MAGIC Evidence Ecosystem Foundation, Doudecim and the Future Evidence Foundation, we are developing a living framework for evidence synthesis. The living framework will continually identify and incorporate new studies to guide optimal decision-making.

The Partnership’s main resource is a living database of randomised trials investigating diabetes treatment drugs in people with type 2 diabetes. 

The dataset contains ~850 trials based on the inclusion and exclusion criteria and continues to be updated. The search is run monthly. The results from the search are screened in duplicate. The identified new trials have their characteristics and outcomes extracted and are assessed for risk of bias all done in duplicate, and the new data is added to the dataset.

For more details on the dataset and the analyses please read the protocol

‍The dataset and corresponding network meta-analyses (NMAs) have been used in a variety of publications over the last 7 years: 

You can get involved in our global partnerships by:

In this partnership, we are currently looking for partners to cost-share and over time also for partners to contribute effort to expand the scope.