HPV Living Evidence Partnership

Taking the next steps to eliminate cervical cancer

 

We’re working with governments across Africa to improve coverage of the life-saving HPV vaccine for young women and girls in low- and middle-income countries (LMICs).

 

 

Challenge

Bringing a life-saving vaccine to those who need it most

Cervical cancer is a leading cause of cancer death for women in LMICs. Despite the availability of a safe, effective, single-dose HPV vaccine, coverage in these areas remains critically low due to delivery challenges.

Those working to improve HPV vaccine roll-out are asking the same questions in different contexts, like:

Delivery strategies

What delivery strategies work best in schools and/or rural areas?

Trust Building

How do we build trust, demand, and uptake in underserved communities?

Best practices

What are best practices related to timing, messaging, and coordination?

The HPV Living Evidence Partnership is identifying evidence-based approaches that address these challenges and drive high, sustainable, equitable coverage of HPV vaccination.

EVidence RESOURCes

A dynamic evidence system made for decision-makers

Access the current HPV living evidence repository, evidence maps, protocols, reports, living systematic review protocols, and upcoming decision-support tools in one place.

Living evidence repository and interactive maps

An easy-to-search living library and interactive maps of HPV vaccine delivery evidence from Low- and Middle-Income Countries.

Previous Versions

Earlier versions are available for reference.

Version 1.0 — December 2025

Living systematic reviews

Living systematic reviews answering priority questions facing HPV vaccine delivery decision-makers in Low- and Middle-Income Countries.

In development

  • LSR 3: Financial and economic cost of HPV vaccine delivery
  • LSR 4: Cost effectiveness of HPV vaccine delivery strategies
  • LSR 5: Leveraging traditional and religious leaders in design and demand generation
  • LSR 6: Integrating health services alongside HPV vaccination
  • LSR 7: Embedding HPV vaccination into adolescent health checks or life-course milestones
  • LSR 8: Integrating HPV vaccination into routine EPI delivery

Decision Support Tools

Coming Soon - Evidence summaries, briefing notes, and guides tailored to specific, country-level needs 

Leadership

Country leaders are at the heart of our partnerships

We’re guided by two governance bodies:

Steering group

Country decision-makers, implementers, and technical leads who define our priorities and shape how we package and share evidence.

See all Steering Group Members

Advisory Group

Global technical and delivery experts who ensure our work is aligned, high-quality, and relevant.

Join us in this vital work

Are you working on HPV vaccine coverage as a…

Country team

with pressing delivery questions?

Synthesis Group

ready to contribute to living reviews?

Funder or partner

supporting HPV vaccine programs?

We’re onboarding new country partners as we grow this project. Reach out to Fumane Lekoala at hello@aliveevidence.org for more information.

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